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Table 2 Application of the RE-AIM framework to evaluate integration of PrEP delivery in into public health FP clinics

From: Integrating PrEP delivery in public health family planning clinics: a protocol for a pragmatic stepped wedge cluster randomized trial in Kenya

Domain

Measurement level

Project specific outcome measures

Reach

Individual

â–ª Proportion of women screened for HIV risk and PrEP

â–ª Number and proportion of at-risk persons initiated on PrEP

Clinic

â–ª Characteristics of implementing clinics

Effectiveness

Individual

â–ª Incident HIV infection among PrEP users

â–ª Detectable tenofovir levels in randomly collected DBS from PrEP users

â–ª Client opportunity costs (e.g., clinic wait time)

Program

â–ª Cost and budget impact from the pragmatic perspective

Adoption

Individual

â–ª PrEP continuation

Clinic

â–ª Number and % of clinics initially approached implementing PrEP in FP clinics

â–ª Number and % of trained clinical FP staff who delivered PrEP at least once

Implementation

Provider

â–ª Number and % of trained appropriately initiated on PrEP

â–ª Consistency of implementation across staff (assessed by patient actors)

â–ª Opportunity costs (e.g., Workload, impact on other services)

Clinic

â–ª Number of clinics regularly completing MOH PrEP M & E tools and report PrEP

â–ª Number and proportion of clinics in which screening for HIV risk and PrEP regularly documented.

â–ª Proportion of women testing is documented

Maintenance

Individual

â–ª 3- and 6-month PrEP continuation rates

Clinic

â–ª Number of FP clinics implementing PrEP FP 6 months, 12 months after scale back of technical assistance

â–ª Number of clinics with PrEP listed in the service charter