Table 1 CFIR and TDF domains relevant for PrEP implementation and those selected to build the questionnaire
| Â | Definition | Included in the survey | Relevant theme in qualitative analysis |
|---|---|---|---|
I. Intervention characteristics | |||
 Evidence strength and quality | HCPs’ perceptions of the quality and validity of evidence support the belief that PrEP will have desired outcomes | Yes | Yes |
 Relative advantage | HCPs’ perception of the advantage of implementing PrEP versus an alternative solution | Yes | Yes |
 Adaptability | The degree to which PrEP can be adapted, tailored, refined, or reinvented to meet local needs | Yes | Yes |
 Complexity | Perceived difficulty of implementation, reflected by duration, scope, radicalness, disruptiveness, centrality, and intricacy and number of steps required to implement | Yes | Yes |
 Cost | Costs of PrEP and costs associated with implementing PrEP include investment, supply, and opportunity costs | Yes | Yes |
II. Outer setting | |||
 Patient needs and resources | The extent to which people’s need for PrEP is recognized by HCP and barriers and facilitators to meet those needs | Yes | Yes |
 Cosmopolitanism | The degree to which the clinics are networked with other external organizations | No | Yes |
 Peer pressure | Pressure from community organizations ot other external organizations to implement PrEP | No | Yes |
 External policies and incentives | Social, political and economic influences over PrEP implementation | No | Yes |
III. Health systems | |||
 Attitudes | Attitudes of HCP regarding the preparedness of the health system to implement PrEP | Yes | Yes |
 Concerns | Concerns of HCP regarding the preparedness of the health system to implement PrEP | Yes | Yes |
 System architecture | The administrative design of Colombian health system or interacting systems that may influence PrEP implementation | No | Yes |
 Funding priorities | Manager’s perception regarding the degree to which funding agent preferences and priorities influence implementation | No | Yes |
 Available resources | The level of resources at health system level needed for implementation of PrEP | No | Yes |
IV. Characteristics of individuals | |||
 Knowledge | HCP are aware of PrEP as an HIV prevention strategy and are familiar with the delivery of PrEP components | Yes | Yes |
 Beliefs about capabilities/self-efficacy | The self-confidence of HCP in performing activities related to PrEP and implementing PrEP | Yes | No |
 Professional role/compatibility | The extent to which PrEP implementation will be/is perceived by HCP as part of their work or responsibilities or compatible with their work | Yes | Yes |
 Social influences | Peer opinions about PrEP that may influence the implementation of PrEP | Yes | No |
 Control | HCP perceptions that they have control over the decision to offer PrEP care | Yes | No |
 Individual stage of change | HCP intentions to offer PrEP care or advocate for PrEP in the clinic | Yes | No |
 Beliefs about consequences | It refers to HCP beliefs about the value of PrEP, consequences, rewards or incentives for managing people in PrEP | Yes | Yes |
V Inner setting | |||
 Structural characteristics | The social architecture, age, maturity, and size of the clinics | No | Yes |
 Networks and communications | The nature and quality of webs of social networks and the nature and quality of formal and informal communications within the clinics | No | Yes |
 Culture | Norms, values, and basic assumptions of each clinic | No | Yes |
 Tension for change | The degree to which managers/clinic directors perceive the current situation as intolerable or needing change | No | Yes |
 Compatibility | The degree how PrEP fits with existing workflows | No | Yes |
 Relative priority | Manager perception of the importance of the implementation within the organization | No | Yes |
 Readiness for implementation | Tangible and immediate indicators of organizational commitment to its decision to implement PrEP | No | Yes |
 Leadership engagement | Commitment, involvement, and accountability of leaders and managers with the implementation of PrEP | No | Yes |
 Available resources | The level of resources at clinical level needed for implementation of PrEP | No | Yes |
 Access to knowledge and information | Ease of access to information and knowledge about PrEP and how to incorporate it into work tasks | No | Yes |
VI Process | |||
 Planning | Existence of any plan to implement PrEP in the clinic | No | Yes |
 Engaging | Strategies to engage populations at risk and other leaders in PrEP | No | Yes |
 Executing | Experience of implementation of PrEP | No | No |
 Evaluating | Evaluation of implementation of PrEP | No | No |