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Table 1 Importance scores and latent class membership for the highest-ranked constructs within each domain and site characteristics by class

From: Best–worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy

Highest-ranked constructs within each domain

% (95% CI)

Latent class %

1

2

Domain: Outer setting

 1. Patient needs and resources-bio-psychosocial factorsa

41.7 (38.1, 45.3)

42.7

38.6

 2. External policy and incentives

33.1 (26.0, 40.2)

14.4

49.5

 3. Peer pressure

14.9 (8.6, 21.3)

31.8

2.4

 4. Social determinants of healtha

6.8 (4.9, 8.7)

7.1

6.3

 5. Cosmopolitanism

3.5 (0.9, 6.1)

4.0

3.1

 Latent class membership

 

44.5

55.5

Site characteristics by latent class membership

  Implemented

 

85.7

70.0

  Academic medical center

 

71.4

60.0

Domain: Inner setting

 1. Leadership engagement

16.6 (15.4, 17.7)

15.2

19.6

 2. Available resources

16.1 (15.1, 17.1)

15.3

15.1

 3. Implementation climate

13.9 (12.3, 15.6)

11.3

15.6

 4. Readiness for implementation

11.4 (9.2, 13.7)

12.4

5.4

 5. Relative priority

10.3 (7.4, 13.2)

8.3

13.9

 Latent class membership

 

76.5

23.5

Site characteristics by latent class membership

  Implemented

 

69.2

100.0

  Academic medical center

 

76.9

25.0

Domain: Characteristics of individuals

 1. Knowledge and beliefs about the intervention

49.9 (45.8, 54.0)

30.6

52.4

 2. Self-efficacy

23.5 (18.4, 28.5)

4.9

25.3

 3. Individual stage of change

18.0 (12.1, 23.9)

40.8

12.2

 4. Other personal attributes

5.4 (2.7, 8.2)

3.1

7.8

 5. Individual identification with organization

3.1 (0.2, 6.0)

20.5

2.2

 Latent class membership

 

17.2

82.8

Site characteristics by latent class membership

   

  Implemented

 

66.7

78.6

  Academic medical center

 

33.3

71.4

Domain: Intervention characteristics

 1. Evidence strength and quality

27.9 (25.9, 29.8)

24.0

29.0

 2. Relative advantage

21.1 (17.0, 25.2)

27.8

16.3

 3. Cost

17.3 (13.4, 21.1)

6.2

22.1

 4. Complexity

13.2 (9.9, 16.6)

14.4

10.6

 5. Ability of the healthcare system to educate individuals receiving care, families, clinicians a

8.0 (5.0, 11.0)

2.6

12.4

 Latent class membership

 

34.7

65.3

Site characteristics by latent class membership

  Implemented

 

83.3

72.7

  Academic medical center

 

33.3

81.8

Domain: Process

 1. Champions

26.9 (23.2, 30.6)

30.6

25.9

 2. Engaging

20.3 (16.1, 24.5)

29.5

10.0

 3. Formally appointed internal implementation leaders

17.0 (11.5, 22.4)

3.0

31.0

 4. Opinion leaders

16.2 (11.5, 21.0)

18.4

10.8

 5. Planning

10.9 (8.2, 13.7)

15.7

8.5

 Latent class membership

 

44.9

55.1

Site characteristics by latent class membership

  Implemented

 

62.5

88.9

  Academic medical center

 

75.0

55.6

  1. aConstructs from the Genomic Medicine Integrative Research (GMIR) Framework