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Table 2 Estimated effect (EE) and effect size (ES) of change in longitudinal outcomes between program baseline (Q0) and active implementation (Q3)

From: Expanding access to medications for opioid use disorder in primary care clinics: an evaluation of common implementation strategies and outcomes

  Overall Start-up clinics Scale-up clinics Scale-up vs. start-up
Reach
Number of patients with OUD
  EE (95% CI) 25.02 (−296.90, 346.94) 10.84 (−516.00, 537.68) 47.21 (−777.98, 872.40) 36.37 (−1314.97, 1387.72)
  ES (95% CI) 0.11 (−1.34, 1.56) 0.05 (−2.33, 2.42) 0.21 (−3.51, 3.93) 0.16 (−5.92, 6.25)
Number patients prescribed MOUD
  EE (95% CI) 12.86 (5.45, 20.28) 9.73 (−2.42, 21.89) 17.76 (−1.25, 36.77) 8.02 (−23.14, 39.19)
  ES (95% CI) 0.19 (0.08, 0.31) 0.15 (−0.04, 0.33) 0.27 (−0.02, 0.55) 0.12 (−0.35, 0.59)
Percent of patients prescribed MOUDa
  EE (95% CI) 11.98 (7.76, 16.20) 22.60 (16.05, 29.15) −4.63 (−7.87, −1.38) −27.23 (−34.51, −19.94)
  ES (95% CI) 0.27 (0.18, 0.37) 0.51 (0.37, 0.66) −0.11 (−0.18, −0.03) −0.62 (−0.78, −0.45)
Adoption
Number of prescribers
  EE (95% CI) 1.24 (0.90, 1.59) 2.18 (1.61, 2.75) −0.23 (−1.12, 0.67) −2.41 (−3.87, −0.95)
  ES (95% CI) 0.04 (0.03, 0.04) 0.06 (0.05, 0.08) −0.01 (−0.03, 0.02) −0.07 (−0.11, −0.03)
Number of x-waivered prescribers
  EE (95% CI) 1.40 (1.23, 1.56) 1.55 (1.28, 1.82) 1.16 (0.74, 1.59) −0.39 (−1.08, 0.31)
  ES (95% CI) 0.22 (0.20, 0.25) 0.25 (0.21, 0.30) 0.19 (0.12, 0.26) −0.06 (−0.18, 0.05)
Number of active x-waivered prescribers
  EE (95% CI) 1.32 (1.25, 1.40) 1.54 (1.42, 1.66) 0.99 (0.81, 1.18) −0.54 (−0.85, −0.24)
  ES (95% CI) 0.34 (0.32, 0.36) 0.40 (0.37, 0.43) 0.26 (0.21, 0.31) −0.14 (−0.22, −0.06)
Percent of x-waivered prescribers
  EE (95% CI) 3.52 (3.43, 3.61) 2.41 (2.27, 2.56) 5.25 (5.02, 5.48) 2.84 (2.46, 3.21)
  ES (95% CI) 0.10 (0.10, 0.10) 0.07 (0.07, 0.07) 0.15 (0.14, 0.16) 0.08 (0.07, 0.09)
Implementation quality
IMAT Implementation quality
  EE (95% CI) 0.53 (0.52, 0.55) 0.59 (0.56, 0.61) 0.45 (0.41, 0.49) −0.14 (−0.20, −0.07)
  ES (95% CI) 0.68 (0.66, 0.70) 0.75 (0.72, 0.78) 0.58 (0.53, 0.63) −0.18 (−0.26, −0.09)
  1. aPrimary outcome; EE and ES in bold indicated 95% CI did not cross zero