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Table 1 Core and periphery components, procedures, and visits of same-day antiretroviral therapy

From: Key population-led community-based same-day antiretroviral therapy (CB-SDART) initiation hub in Bangkok, Thailand: a protocol for a hybrid type 3 implementation trial

SDART core components

Adapted periphery components

SDART procedures

Timepoint

Initiation visit: day 0

Follow-up visit: day 14

Refer-out: day 45

Long-term follow-up: day 46–day 730

Interactive counseling to assist clients to make an informed decision regarding ART initiation and lifelong adherence as well as to set positive treatment and self-care goals in order to achieve viral suppression

Increasing the role of KP lay provider in leading ART initiation service in addition to their case management and support role; adding option to return to CBO for point-of-care viral load testing at 6 months after ART initiation

CB-SDART eligibility assessment

✓

   

Psychosocial readiness and willingness assessment

✓

   

Ongoing counseling and adherence support provided by peer navigators

✓

✓

✓

✓

Screening to rule out serious opportunistic infections before ART initiation

Chest X-ray and selected laboratory testing conducted outside of the clinic; adding point-of-care CD4 count testing to aid ART initiation and physical examination led by KP lay providers under the remote supervision of physicians

Symptomatic screening

✓

   

Sample collection for baseline laboratory testing, STI sample collection (if accepted)

✓

   

Chest X-ray

✓

   

Informing baseline laboratory test results

 

✓

  

ART initiation within the same day of HIV diagnosis for clients who are ready and willing to start ART without clinical complications, if possible

Adding ART initiation and follow-up options, including in-person at the CBOs or via telehealth, with KP lay providers or physicians; adding ART home delivery option

ART prescription

✓

   

Management of adverse drug events

 

✓

  

ART modification (if required) and refill

 

✓

  

Referral system at the ready to assist clients to change their facility coverage according to their national health insurance and in referral process

KP lay providers assisting clients in navigating the health system and in the referral process

Refer for OI investigation (for clinically ineligible clients)

✓

   

Change in facility coverage to utilize the national health insurance (if requested)

✓

   

Warm-hand off (if requested)

  

✓

 
  1. SDART Same-day antiretroviral therapy, CB-SDART Community-based same-day antiretroviral therapy, ART Antiretroviral therapy, CBO Community-based organization, STI Sexually transmitted infection, KP Key population, OI Opportunistic infection