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Table 2 SAIA-TB primary and secondary outcomes

From: Systems analysis and improvement approach to optimize tuberculosis (SAIA-TB) screening, treatment, and prevention in South Africa: a stepped-wedge cluster randomized trial

SAIA-TB primary and secondary outcome variables

TB indicator (variable)

Numerator/denominator

TB screeninga

#screened with WHO symptom screen

# target population

TB evaluation

# receiving a diagnostic evaluation (GXP/LAM)

# positive screening

TB diagnosis

# diagnosed with TB (GXP/LAM/clinical)

# who completed a diagnostic evaluation

Linkage to care for TPTa

# initiating TPT

# negative diagnostic evaluation + eligible for TPT

Linkage to care for TB diseasea

# initiating TB treatment

# positive diagnostic evaluation

Successful TPT outcome

# completing TPT

# initiating TPT

Successful TB outcomeb

# cure or complete treatment for TB disease

# initiating TB treatment

TB-free survival

# TB-free (CXR/GXP) 12 months

after initiating TPT or TB disease treatment

# successful outcomes for TPT or TB disease

  1. CXR Chest x-ray, GXP GeneXpert, LAM, Urine lipoarabinomannan
  2. aPrimary outcome variable
  3. bWHO definition