Table 3 Facilitators to implementing TB preventive therapy into a comprehensive TB program in a rural setting by CFIR domain and construct

Intervention characteristics

 Start with people who are easy to access and who should already be getting TPT—including people who are living with HIV and pregnant women

Design quality and packaging

 De-centralized medication collection points such as the Central Chronic Medicines Dispensing and Distribution (CCMDD) models

Design quality and packing/networks

 Utilizing existing medication pre-packaging programs to decrease congestion at hospitals and clinics

Design quality

Inner setting

 Clinics are enthusiastic to engage and follow guidelines

Readiness for implementation

 Dedicated nursing staff exist to focus on TB at the hospital

Readiness for implementation

 WhatsApp groups and other communication channels among clinical teams already exist to communicate about stock supply, scheduling, patient linkage, etc

Implementation readiness/networks and communications

 Access to communities and households via existing ward-based outreach teams and CHWs

Implementation readiness, available resources

 Existing triage processes within clinics where individuals are supposed to be screened for TB and asked about contacts

Readiness for implementation

 Existing journal clubs at hospital to discuss guidelines, implementation, and evidence

Access to knowledge

 Existing partnerships between the clinics and hospital; including medical officers visiting clinics regularly for complex patients

Networks and communication

Process

 Household champions are easy to identify in the community (i.e., grandmothers)

Champions

 The ability of identified community members, including chiefs to organize and inform the masses

Champions