Adaptations of evidence-based trauma-focused interventions for children and adolescents: a systematic review
Implementation Science Communications volume 3, Article number: 108 (2022)
Rates of potentially traumatic events (PTEs) and other forms of adversity among children are high globally, resulting in the development of a number of evidence-based interventions (EBIs) to address the adverse outcomes stemming from these experiences. Though EBIs are intended to be delivered according to set parameters, these EBIs are frequently adapted. However, little is known about existing adaptations of EBIs for children who experienced PTEs or other adversities. As such, this review aimed to determine: (1) why existing EBIs designed to address PTEs and other adversities experienced by children are adapted, (2) what processes are used to determine what elements should be adapted, and (3) what components of the intervention are adapted.
Nine academic databases and publicly available search engines were used to identify academic and grey literature. Initial screening, full-text review, data extraction, and quality determinations were completed by two members of the research team. Data were synthesized narratively for each adapted EBI by research question.
Forty-two studies examining the adaptations of nine different EBIs were located, with Trauma-Focused Cognitive Behavioral Therapy and Cognitive Behavioral Intervention for Trauma in Schools being the most commonly adapted EBIs. Most frequently, EBIs were adapted to improve fit with a new population and to address cultural factors. Most commonly, researchers in combination with others made decisions about adapting interventions, though frequently who was involved in these decisions was not described. Common content adaptations included the addition of intervention elements and the tailoring/tweaking/refining of intervention materials. Common contextual adaptations included changes to the intended population, changes to the channel of treatment delivery, and changes to who administered the intervention.
Most published studies of EBI adaptions have been developed to improve fit and address cultural factors, but little research is available about adaptations made by clinicians in day-to-day practice. Efforts should be made to evaluate the various types of adaptations and especially whether adaptations improve access to services or improve child outcomes in order to ensure that all children exposed to trauma can access effective treatment.
The protocol for this systematic review was published with PROSPERO (CRD42020149536).
Childhood exposure to potentially traumatic events (PTEs) and other forms of adversity represents a significant global public health problem. Examples of PTEs include experiencing violence, physical abuse, sexual abuse, a serious accident, serious physical illness, the death of someone close, or a natural disaster . Adversity is conceptualized more broadly than PTEs and includes other forms of stressful or difficult circumstances such as poverty, discrimination, living with a caregiver who has mental illness or substance use problems, and other forms of adverse childhood experiences (ACEs [2, 3]). Recent research has demonstrated that PTEs and other forms of adversity are highly prevalent among children. Specifically, in a study of 4000 children conducted in the USA, 60.8% of children had experienced direct exposure to violence, abuse, or crime within the past year .
If PTEs or other forms of adversity are not addressed, these events can have negative effects into adulthood, including poorer mental and physical health, and increased risky substance use and sexual behaviors . Given high rates of PTEs and subsequent negative outcomes stemming from these events, a number of evidence-based interventions (EBIs) have been developed for children, such as Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), Cognitive Behavioral Therapy, and Child Parent Psychotherapy .
Existing EBIs have been modified or adapted for a number of reasons. A recent global systematic review of public health interventions found that the most common reasons for adapting interventions were “the need for cultural appropriateness (64.3%), focusing on a new target population (59.5%), and implementing in a new setting (57.1%). Common adaptations were content (100%), context (95.2%), cultural modifications (73.8%), and delivery (61.9%)” .
Given the breadth of available EBIs, systematic reviews have been conducted to examine these interventions. One systematic review examining EBI adaptations did not focus on EBIs to treat child traumatic stress , while others have examined EBIs and other interventions for children who have experienced traumatic stress, without discussing the nature of included adapted interventions in depth or while focusing on a specific target population [8–11]. These reviews note that understanding the types of adaptations that are made is an important area for further research. Thus, this review aims to answer the following research questions:
Why are existing EBIs designed to address PTEs and other forms of adversity experienced by children being adapted?
What processes are used to determine which elements of the intervention should be adapted?
What components of the intervention are adapted?
Pre-registration and reporting guidelines
The protocol for this review and subsequent amendments to this review (e.g., minor updates to research questions) were published with PROSPERO . This systematic review adheres to the PRISMA 2020 guidelines for reporting systematic reviews  and the PRISMA 2020 Checklist for systematic reviews is included as an Additional file 1.
The full search strategy for this review is available in Additional file 2. Nine academic databases were searched on October 14, 2019: Applied Social Sciences Index & Abstracts, Embase, ProQuest Dissertations & Theses Global, PsycINFO, PubMed, Scopus, Social Services Abstracts, Sociological Abstracts, and Web of Science. The search strategy was created by compiling text words and controlled vocabularies (when allowed by the database) within each database that covered four areas: evidence-based interventions, trauma, the population of interest (i.e., children and adolescents), and adaptation. The search was validated using a list of pre-identified studies meeting the inclusion criteria for this review. Pre-identified studies were located by searching the names of several existing EBIs developed to address trauma, which were located through the National Child Traumatic Stress Network’s list of interventions for trauma , and the term “adaptation.” Additionally, a supplementary search was conducted on August 31, 2021, in PubMed using the same search terms as the original search to capture studies that may have been published since the original search date. Both searches were developed and run by the first author (BL).
In addition to academic databases, Google was used to identify potentially relevant grey literature. The first author (BL) searched Google using different combinations of terms used in the academic databases and reviewed the first three-five pages of results for potentially relevant articles for each set of search terms. Further, a list of conference presentations on EBI adaptations was compiled from the National Child Traumatic Stress Network’s list of interventions for trauma . The authors of these presentations were contacted to determine if manuscripts or reports had been written based on the presentations.
Once included studies were determined from the initial full-text review (process outlined below), all included studies had their references searched to identify additional potential studies for inclusion. Further, all included studies were forward searched (i.e., studies that cited included studies were screened for potential inclusion). This process was repeated for any study found through this method until no new studies could be located. In both instances, the first author (BL) completed the search, with all potential new articles for inclusion being reviewed by the second author (AN).
Screening based on study inclusion and exclusion criteria
Studies located through searches in academic databases and non-academic search engines were downloaded to EndNote where duplicates were removed. Following this, the remaining studies were uploaded to Rayyan (an online tool for systematic review management) for screening . During the initial screening, which occurred at the title and abstract level, the first author (BL) screened 100% of the studies, while the second author (AN) screened 20% of the studies. This percentage was purposively chosen based on the methods of other high-quality systematic reviews. The goal of this initial screening was to briefly assess studies to determine if there was any likelihood they may be relevant to the review, with both authors prioritizing sensitivity in screening to ensure that no potentially relevant studies were missed. Upon completion of this screening, both authors met to discuss and resolve discrepancies. Once all discrepancies were resolved, full texts of the remaining studies were located. These full texts were screened using the same process as the initial screening (i.e., BL reviewed 100% of full texts, and AN reviewed 20% of full texts, with discrepancies resolved through further review of full texts and discussion until a consensus could be reached). For each step of the process, the third author (JL) was available to help resolve discrepancies. However, BL and AN were able to resolve all discrepancies without consultation with JL.
To be included in the review, the article had to meet the following criteria:
A full text is available.
Is in English. Articles not published in English were excluded, as there were no resources available for translation of articles.
Is empirical. Articles with an abstract only, reviews, or think pieces were excluded.
Evaluates an intervention that was developed to address PTEs and traumatic stress or has been adapted to address PTEs and traumatic stress.
Evaluates an adaptation of an evidence-based intervention. There are different conceptualizations of what constitutes an “evidence-based” intervention. For this review, an intervention was considered “evidence-based” if it was registered with the California Evidence-Based Clearinghouse  or Blueprints for Healthy Youth Development .
Evaluates an EBI for children (18 and under). This EBI could have been developed specifically for children or adapted for use with children.
The adaptation to the EBI is clearly described and provided similarly to all children in the study.
Contains at least one child mental health outcome.
Does not contain solely case studies.
In instances where both a thesis and journal article are available about the same study, only the journal article was included. Further, in instances where primary data is duplicated in multiple publications, only one study was included.
We conducted data extraction in Excel. Items for extraction included the following main topics: basic study information (research question, theoretical framework, etc.), methods (sampling strategy, data analysis, etc.), adaptation reasons (goal of adaptation, type of adaptation), adaptation processes (how decisions to adapt were made, specific adaptations made, etc.), results (participant characteristics; changes in mental health outcomes, such as post-traumatic stress), and next steps (future research and policy implications). Items chosen for extraction related to adaptations were from the Framework for Reporting Adaptations and Modifications – Expanded (FRAME ). BL completed extraction for 100% of included studies, while AN completed extraction for 20% of included studies. 20% was selected purposively based on best practices for systematic reviews. All discrepancies in extraction were resolved through further review of the article and discussion among BL and AN. Though JL was available to help address discrepancies if needed, BL and AN were able to address all discrepancies among themselves.
To our knowledge, no validated measure exists to assess the risk of bias specifically in studies that have made adaptations. As such, a general measure to assess bias, the Evidence Project Risk of Bias Tool was used . BL and AN conducted risk of bias assessments. Both authors did not have formal training on the use of this measure, but engaged in a thorough review of the literature on the measure to ensure that it was being used appropriately. BL conducted 100% of risk of bias assessments, while AN conducted 20% of risk of bias assessments to ensure reliability. 20% was selected purposively based on best practices for systematic reviews.
For each EBI, data were narratively synthesized for each adapted EBI by research question using the agreed upon extraction documents described previously.
Overview of results
Forty-two studies examining the adaptations of nine different EBIs were included in this systematic review [20–61]. Please see Fig. 1 for a flow diagram of our review and selection process. Many of these were published between 2011-2015 [21, 22, 24–29, 31, 41–44, 46, 48, 50, 57, 60] and were conducted in the USA [20, 22, 23, 30–42, 45, 46, 48, 49, 57–61]. The average sample size in these studies was 55.3 (SD=51.4). The most commonly adapted EBIs were TF-CBT [20–33, 61] and Cognitive Behavioral Intervention for Trauma in Schools [34–42]. See Table 1.
Across all EBIs, the decision to adapt an intervention was most often made by the researcher in collaboration with others [21, 23, 26–30, 34, 35, 37, 38, 40–49, 56, 57]. The most common reason for adaptations was to improve fit with recipients [20, 23, 24, 34, 43–54, 57–62]. The second most common reason for adaption was to address cultural factors, a subcategory of improving fit , to meet the needs of diverse racial and ethnic populations. This was listed as the main reason for adaptation [21, 25, 30, 35–38, 40] or one of the main reasons for adaptation [26–29, 41, 42, 56] in fifteen articles. The most common types of contextual adaptations were changes to the intended population [34, 35, 43–54, 57–60, 62], such as a treatment designed for adults being adapted to children; changes to format [21, 23, 25, 28, 29, 31–33, 37, 39], such as changing the channel of delivery for a particular intervention component from in-person to virtual; and changes in personnel [26–29, 31, 32, 34, 39, 56], such as changing who an intervention is designed to be administered by from a therapist to a lay worker. The most common content adaptations were adding elements [20, 21, 23, 24, 26–29, 31–37, 40–56, 58, 59, 61]; tailoring, tweaking, or refining of materials [21, 23, 25–27, 29, 30, 33–38, 40–52, 56, 58]; shortening or condensing intervention elements [20–22, 41–50, 57]; lengthening or extending intervention elements [21, 26, 34, 35, 37, 38, 41, 42, 58, 59]; and removing or skipping elements [22, 24, 34, 36, 39, 40, 57]. See Table 2.
Results of research questions are summarized by EBI below, with detailed information on each EBI presented in Tables 3, 4, 5, 6, and 7. Though FRAME includes adaptations made to Training and Evaluation, and Implementation and Scale-Up, these were infrequently made or not reported on by study authors. Thus, Tables 3, 4, 5, 6, and 7, and the summaries below focus on content and contextual adaptations. See Additional file 3 for study quality ratings.
Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)
Fifteen adaptations of TF-CBT were located [20–33, 61]. See Table 3. Commonly, who participated in the decision to adapt TF-CBT was not described [20, 22, 25, 31–33, 61]. Across all TF-CBT adaptations, the most common content adaptations were adding elements [20, 21, 23, 24, 26–29, 31–33, 61] and tailoring/tweaking/refining intervention components [21, 23, 25–27, 29, 30, 33], and the most common contextual adaptations were changes to format [21, 23, 25, 28, 29, 31–33] and personnel [26,27,28,29, 31, 32].
The most common reason for adaptation was to address cultural factors, with interventions being tested in Jordan , the Democratic Republic of Congo [25, 29], Zambia [26, 27], and with Hispanic children in the USA . Given the aim of addressing cultural factors, many of these interventions engaged in tailoring/tweaking/refining to adapt language, examples, analogies, songs, or stories to fit with the culture in which they occurred [21, 25–27, 29, 30]. Several of these interventions made contextual adaptations by switching the format of treatment to group delivery [21, 25, 29]. Additionally, several interventions made changes to personnel, by adapting TF-CBT to be delivered by lay counselors [26, 27, 29], which was an element also tied to the goal of increasing the feasibility of these interventions in different cultural contexts where mental health clinicians may be less available.
TF-CBT was also adapted primarily to improve feasibility in other adaptations. In two instances, TF-CBT’s format was adapted to a stepped format, in which the first step was caregiver-led, with the second clinician-led step being only for those who did not respond to the first step of treatment [31, 32]. Another study shortened/condensed TF-CBT by reducing the number of sessions and removed/skipped elements by removing the trauma narrative to determine if these changes affected the efficacy of TF-CBT . In a final adaptation to improve feasibility, the format (channel of treatment delivery) of TF-CBT was changed to be delivered through telehealth, with materials adapted to fit an electronic setting .
Finally, TF-CBT was adapted to improve fit [20, 23, 24, 28, 61]. In four instances, adaptations were related to traumatic loss [20, 24, 28, 61], with researchers in two studies [20, 28] making additional changes to a previous adaptation of TF-CBT to address traumatic loss . Adaptations included adding elements to address traumatic loss [20, 24, 28, 61], condensing the number of grief module sessions , and removing parent sessions . A further intervention aimed to improve fit with adolescents in the juvenile justice system by making adaptations to address the setting, such as tailoring/tweaking/refining the imaginal desensitization exercises. The typical format of parent interactions was also changed from in person to phone or videoconferencing, as these could not happen outside the correctional facility .
Cognitive Behavioral Intervention for Trauma in Schools (CBITS)
Nine adaptations of CBITS were located [34–42]. See Table 4. In the majority of studies, adaptations were made in partnership with teams, including community members [34, 35, 37, 38, 40–42]. Across all CBITS adaptations, the most common content adaptations were tailoring/tweaking/refining [34–38, 40–42], adding elements [34–37, 40–42], and lengthening/extending [34, 35, 37, 38, 41, 42]. Contextual adaptations occurred equally across format [37, 39], setting [34, 35], personnel [34, 39], and population [34, 35].
A primary aim of five interventions was to address cultural factors, focusing on immigrant populations [35, 36, 38] and on American Indian populations [37, 40]. Adaptations varied, but most commonly content adaptations included tailoring/tweaking/refining to ensure material was culturally appropriate [35–38, 40], removing/skipping program components (e.g., introductory activities; [36, 40]), and adding/lengthening elements, such as family-related components [35, 36, 38]. An example of a contextual adaptation was changing the setting of the intervention from a school to the community .
The primary adaptation made in two studies was the addition of a family component that was designed not only to educate family members on CBITS, trauma, and helping their children through treatment, but was also designed to improve parent functioning [41, 42]. In contrast to CBITS, this family component was required and involved family members attending sessions where they were offered information on topics such as coping strategies and parenting [41, 42]. In both instances, tailoring/tweaking/refining took place to address cultural factors, with adaptations including the addition of culturally relevant examples; the intervention being lengthened or shortened depending on the needs of those involved; and materials from other approaches being integrated into treatment [41, 42].
One study adapted CBITS to create a new intervention – Support for Students Exposed to Trauma (SSET ). SSET is designed to improve the feasibility of CBITS by having the intervention be delivered by those without clinical training. Content adaptations involved the removing of sessions, with contextual adaptations outside who delivered the intervention involving changing from a session format to a lesson plan format and changing imaginal exposure to be in a curricular format . SSET itself has now been classified as having promising research evidence by the California Evidence Based Clearinghouse .
One intervention was adapted to improve fit with females involved in child welfare. Content adaptations included removing the teacher session, adding sessions, lengthening sessions, and tailoring/tweaking/refining intervention components. Contextual adaptations included changing the setting of the intervention to be delivered in a mental health agency rather than a school, changing the target population, and changing the personnel to two group facilitators .
Prolonged Exposure Therapy (PE)
Eight adaptations of PE were located [43–50]. See Table 5. The goal of all eight of these adaptations was to improve the fit of PE with an adolescent population [43–50]. Who made the decision to adapt the intervention was not listed in articles [43–50], though a manual  cited by study authors described adaptations being made by the research team, therapists, and community members in seven instances [43–49]. The same adaptations were made to tailor PE to adolescents in all but one  of the eight adaptations.
The seven studies following the same adaptations cited several sources for information on the adaptations made [47, 63, 66], but were often not explicit in the article itself about the adaptations made. Adaptations summarized here have been extracted from one of the manuals cited by study authors . Adaptations included the addition of elements, including developmentally appropriate activities and the involvement of caregivers; tailoring/tweaking/refining intervention components, including procedures based on the emotional needs of the adolescent and simplifying language; and shortening session time when needed [43–49]. In the remaining article not following this manual, adaptations to PE were similar and included the addition of developmentally appropriate activities, which could be tailored based on the age of the child, and the involvement of caregivers in treatment .
Given the research supporting this new model, Prolonged Exposure Therapy for Adolescents (PE-A), is now considered to be well supported by the research evidence, the highest rating given by the CEBC .
Narrative Exposure Therapy (NET)
Five adaptations of NET were located [51–55]. See Table 6. In all instances, contextual adaptations included changing the population of NET to a younger population, with the goal being to improve fit with that population, though no article described who participated in the decision to adapt the intervention [51–55]. Though all articles reported adapting NET to KIDNET, a new intervention for children developed from NET, the reported adaptations listed in articles varied. For example, though all articles mentioned adding illustrative, creative elements, such as the introduction of a string for the creation of a lifeline, stones, flowers, and drawings [51–55], just three described adding the use of body positioning to aid in the trauma reenactment [51, 54, 55]. KIDNET is now considered to have promising research evidence supporting its efficacy .
Two adaptations of Multisystemic Therapy (MST) were located [59, 60], with one being an adaptation of standard MST  and one being an adaptation of MST-CAN and MST . See Table 7. Who participated in decisions to adapt was not listed in one study , while in the other researchers made the decision . Researchers in both studies aimed to improve the fit of MST for children involved in the child welfare system [59, 60]. Content adaptations made to MST included lengthening treatment, adding elements to strengthen agency-family relationships, and adding pharmacotherapy when needed . Content adaptations made to MST-CAN and MST involved integrating these interventions into another model (Reinforcement-Based Treatment) to create a new intervention .
One adaptation of SSET (an intervention derived from CBITS) was located. See Table 7. Both the research team and community members were involved in the adaptation. The main contextual adaptation was that those with clinical training led the intervention, though teachers served as co-facilitators. Content adaptations included the tailoring/tweaking/refining of intervention components, including translating materials, as well as the addition of regular parent meetings .
One adaptation of Skills Training in Affective and Interpersonal Regulation (STAIR), an intervention initially developed for adults, was located. See Table 7. STAIR was adapted by researchers and clinicians to improve fit with an adolescent, inpatient population. Specific adaptations included removing the trauma narrative, condensing treatment, giving adolescents the ability to repeat sessions, and re-ordering intervention components by giving adolescents the option to attend sessions out of order .
One adaptation of Seeking Safety (SS) was located (Table 7). Who participated in the adaptation was not explicated in the article, but the intervention, which was initially developed for adults, was adapted to improve fit with adolescent girls with substance use disorders. Adaptations included the addition of two sessions and updates to parents (if agreed upon), and tailoring/tweaking/refining material to talk in the displacement, discuss trauma details, and verbally deliver the material when needed .
Overview of results
This review was the first comprehensive attempt to synthesize published literature on adaptations of EBIs for children who have experienced trauma. In total, 42 studies examining the adaptations of nine different EBIs were located, with TF-CBT and CBITS being the most commonly adapted EBIs. EBIs were most frequently adapted to improve fit with a new population and to address cultural factors. Most commonly, researchers in combination with others made decisions about adapting interventions, though who was involved in these decisions was often not described in articles. Common content adaptations included the addition of intervention elements and the tailoring/tweaking/refining of intervention materials. Common contextual adaptations included changes to the intended population, changes to the channel of treatment delivery, and changes to who administered the intervention.
Implications and directions for future research
The most common reason for adaptation of EBIs was to improve fit with recipients. Specific need to improve fit often stemmed from needing to tailor an intervention to a new population (e.g., a younger population) or setting. This finding is in keeping with other systematic reviews on this topic where researchers found the need to adapt to a new population or setting to be the second and third most common reason for adaptation . Though efforts have been made to adapt a number of EBIs to better fit with recipients, there have been a number of additional proposed adaptations to better fit the needs of LGBTQ youth , African American youth , and youth with autism spectrum disorder [71, 72] that should be evaluated.
The second most common reason for adapting an EBI was to address cultural factors. The need to adapt EBIs to new cultural contexts or to cultural groups is common and was the most common reason found for adapting public health interventions in a systematic review conducted by Escoffery, Lebow-Skelley . Though interventions are increasingly being developed for, and adapted and evaluated in, multiple cultural contexts, many EBIs were developed in the USA and centered on majority (and often White) populations. There is a need to evaluate the efficacy of EBIs for diverse populations and contexts, and when necessary, develop adaptations for additional cultural contexts and populations to fully meet the needs of children who are experiencing trauma globally. For example, adaptations to EBIs to meet the cultural needs of children in China  have already been proposed. However, it is also critical to make decisions about adaptations deliberately based on the available research; for example, there is evidence that many EBIs are equally effective for children from different racial/ethnic backgrounds .
The reason for the adaptations guided the type of adaptation made. For example, when the reason for an intervention was a cultural adaptation, content adaptations were made that included adding culturally relevant material. In some instances, given resource constraints in some settings, contextual adaptations were made, including changing who administered the intervention (e.g., therapist to teacher). This practice of task shifting is a common occurrence in the delivery of mental health services , and is particularly important as the need for mental health services outpaces the capacity of mental health professionals in many countries and communities.
Methods for making decisions on adaptations were often not described, including whether they were made solely based on the authors’ expertise, existing research, needs assessments, consultation with community members, and/or pilot studies, which may be due to space or word limitations for journals. This represents a missed opportunity to share information about how successful adaptations are developed. Future researchers attempting to adapt interventions will benefit from partnering with those delivering and receiving the interventions when developing or evaluating adaptations to make to ensure that these adaptations fully meet the needs of those they are intended for. One avenue for more collaborative decision-making is a community-based participatory research (CBPR) approach  or user-centered design .
Though adaptations are frequently made to interventions, we must avoid the temptation to adapt every EBI for every unique setting or population without understanding how the original model works and for whom adaptations are necessary. Unnecessary adaptation may lead to an overwhelming number of variations with limited ability to understand their relative effectiveness or loss of the original EBI’s core components. This balance between intervention fidelity and adaptations is an ongoing challenge, but perhaps could be easier to navigate if the core components, opportunities for adaptation, and “red lines” for model fidelity (e.g., which adaptations are considered fidelity consistent or inconsistent) were more clearly articulated during EBI development. Often, EBI developers promote the flexibility of their model but also require strict fidelity, making it difficult to know how or when a model can be adapted. More explicit guidance and examples of successful fidelity-consistent adaptations can enhance efforts to scale and spread treatments effectively. Further, with limited resources and a growing number of trauma-focused EBIs, we must prioritize adaptations for populations where data indicate they are not being adequately served by existing EBIs. Research suggests that most EBIs are effective with diverse populations . Specifically, existing EBIs should generally be considered a first line approach even with populations or children that may differ from the EBI research sample(s), even if with minor tailoring that maintains fidelity to the EBI. Use of outcome data on EBIs in practice with diverse populations should be used to inform the decision to develop adaptations.
Though this review published existing academic and grey literature on adaptations, the research on adaptations pales in comparison to how frequently adaptations are likely made in real-world settings (but never evaluated or published). In light of the emphasis on fidelity during training and implementation, as well as possible implicit or explicit power differentials between practitioners and those who conduct and champion the research or implementation, providers may be reluctant to share these adaptations with EBI developers for fear of running afoul of treatment fidelity or certification requirements. This is another reason that further research with practitioners in real-world settings (e.g., using CBPR) is needed to determine what adaptations are being made in practice to EBIs and how these adaptations may affect intervention outcomes and access to services.
It is possible that studies relevant to this review were not located. Specifically, though we did not limit our searches to the English language, we only included studies published in the English language. Further, we excluded studies of EBIs that included people over the age of 18, even in instances where some of the population were 18 or under (e.g., [79,80,81,82,83,84,85]). Finally, it is possible that studies with non-significant results were not published due to publication bias. These studies may have provided additional insight into adaptations of EBIs for children.
The synthesis of adaptations made is also limited by the source articles. Due to space constraints, it is possible that the study authors did not fully report on all aspects of the adaptation process, including who was involved in the adaptations and all of the adaptations that were made. If aspects of adaptation were omitted from articles, these would not have been extracted by our research team, and thus would not be synthesized here. Some of the information missing from articles may have been available in published implementation manuals, however, due to funding constraints, the research team was unable to extract data from these sources, with the exception of the PE-A manual.
This systematic review found that EBIs have been frequently adapted and evaluated for use with children globally. Most published studies of EBI adaptions have been developed to improve fit and address cultural factors. However, little research is available about adaptations made by clinicians in day-to-day practice. Efforts should be made to evaluate the various types of adaptations and especially whether adaptations improve access to services or child outcomes in order to ensure that all children exposed to trauma can access effective treatment.
Availability of data and materials
All data generated or analyzed during this study are included in this published article and its supplementary information files.
Cognitive Behavioral Intervention for Trauma in Schools
Cognitive Behavioral Therapy for Childhood Traumatic Grief
Child Protective Services
Democratic Republic of Congo
Modified Prolonged Exposure
Multisystemic Therapy for Child Abuse and Neglect
Narrative Exposure Therapy
Prolonged Exposure Therapy for Adolescents
Potentially traumatic events
Support for Students Exposed to Trauma
Skills Training in Affective and Interpersonal Regulation
Trauma-Focused Cognitive Behavioral Therapy
United States of America
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Lange, B.C.L., Nelson, A., Lang, J.M. et al. Adaptations of evidence-based trauma-focused interventions for children and adolescents: a systematic review. Implement Sci Commun 3, 108 (2022). https://doi.org/10.1186/s43058-022-00348-5
- Systematic review
- Evidence-based interventions
- Traumatic events
- Mental health